BROOKS, Ky. — For the second time in two days, fire erupted after a CSX train derailment.

Cyclohexane, methyl ethyl ketone, butadiene and alcohol were released following the derailment of 12 cars, according to published reports. No one was injured in the derailment, but several people did go to area hospitals, though they were soon released.

A portion of Interstate 65 was closed because of the derailment.

Footage of the derailment showed large flames and thick black smoke.

A day earlier in Irvine, Ky., fire erupted after butyl acetate leaked from a crashed tank car.

The leak and fire came after four runaway cars struck a pair of locomotives. Some evacuations were ordered after the crash, but no one was injured in the derailment.