Investigators are looking into whether speed played a role in the fatal wreck that left six dead and dozens more injured, CNN reported.
The train derailed about 9:30 p.m. just north of Philadelphia. The train was traveling from Washington to New York.
“We are deeply saddened by the loss of life from Amtrak Northeast Regional Train 188 that derailed north of Philadelphia Tuesday evening,” Amtrak said in a statement.
Amtrak said there were 238 passengers and five crewmembers on the train at the time of the crash. At least 140 people were taken to area hospitals, some in critical condition, according to news reports.
Amtrak service on the Northeast Corridor between New York and Philadelphia has been suspended.